Targeted next generation sequencing in 112 Chinese patients with intellectual disability/developmental delay: novel mutations and candidate gene

Abstract Background Intellectual disability/developmental delay is a complex condition with extraordinary heterogeneity.A large proportion of patients lacks a specific diagnosis.Next generation sequencing, enabling identification of genetic variations in multiple genes, has become an efficient strategy for genetic analysis in intellectual disabilit

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Inhibitory Copulation Effect of Vibrational Rival Female Signals of Three Stink Bug Species as a Tool for Mating Disruption

Stink bugs are major pests in diverse crops around the world.Pest management strategies based on insect behavioral manipulation could help to develop biorational management strategies of stink bugs.Insect mating disruption using vibratory signals is an approach with high potential for pest management.The objective of this work was to investigate th

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Pangenome comparison via ED strings

IntroductionAn elastic-degenerate (ED) string is a sequence of sets of strings.It can also be seen as a directed acyclic graph whose edges are labeled by strings.The notion of ED strings was introduced as a simple alternative to variation and sequence graphs for representing a pangenome, that is, a collection of genomic sequences to be analyzed joi

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